Publications
Publications
14 peer-reviewed papers spanning computational drug discovery, cancer signaling, and molecular modeling (2020-2023).
Protein interactions
2023
Saibu, O. A., Hammed, S. O., Oladipo, O. O., Odunitan, T. T., et al. · Bioorganic & Medicinal Chemistry
Protein-protein interaction and interference of carcinogenesis by supramolecular modifications.
DOI
10.1016/j.bmc.2023.117211
Immunotherapy
2023
Saibu, O. A., Ajayi, T. M., Omoboyowa, D. A., et al. · Arabian Journal of Chemistry
Molecular mechanics and dynamics simulation of CD-47/SIRPα blockade study: a computational study on overcoming immunotherapeutic resistance in pancreatic ductal adenocarcinoma.
DOI
10.1016/j.arabjc.2023.105265
Drug discovery
2023
Saibu, O. A., Singh, G., Omoboyowa, D. A., et al. · Informatics in Medicine Unlocked
Discovery of putative natural compounds inhibitor of the germinant spore receptor CspC in Clostridioides difficile infection: gaining insights via in silico and bioinformatics approach.
DOI
10.1016/j.imu.2023.101339
HER2
2023
Saibu, O. A., Singh, G., Olugbodi, S. A., et al. · Journal of Biomolecular Structure and Dynamics
Identification of HER2 inhibitors from curcumin derivatives using combination of in silico screening and molecular dynamics simulation.
DOI
10.1080/07391102.2023.2175260
Breast cancer
2023
Odunitan, T. T., Saibu, O. A., Apanisile, B. T., et al. · Computers in Biology and Medicine
Integrating biocomputational techniques for breast cancer drug discovery via the HER-2, BCRA, VEGF, and ER protein targets.
DOI
10.1016/j.compbiomed.2023.107737
EGFR
2021
Balogun, T. A., Nureni, I., Olayemi, T. A., ..., Saibu, O. A., et al. · Cancer Informatics
Computational evaluation of bioactive compounds from Colocasia affinis Schott as a novel EGFR inhibitor for cancer treatment.
DOI
10.1177/11769351211049244
HER2
2021
Balogun, T. A., Muhammad, N. I., Saibu, O. A., et al. · Journal of Biomolecular Structure and Dynamics
Discovery of potential HER2 inhibitors from Mangifera indica for the treatment of HER2-positive breast cancer: an integrated computational approach.
DOI
10.1080/07391102.2021.1975570
Drug discovery
2021
Balogun, T. A., Oluwasegun, M. I., Alausa, A., ..., Saibu, O. A., et al. · Future Journal of Pharmaceutical Sciences
Receptor tyrosine kinases as a therapeutic target by natural compounds for cancer treatment.
DOI
10.1186/s43094-021-00346-9
Neurodegenerative disease
2021
Omoboyowa, D. A., Balogun, T. A., Omomule, O. M., Saibu, O. A. · Bioinformatics and Biology Insights
Identification of terpenoids from Abrus precatorius against Parkinson's disease proteins using in silico approach.
DOI
10.1177/11779322211050757
SARS-CoV-2
2021
Omoboyowa, D. A., Balogun, T. A., Chukwudozie, O. S., Nweze, V., Saibu, O. A., Alausa, A. · Biointerface Research in Applied Chemistry
SARS-CoV-2 spike glycoprotein as inhibitory target for in silico screening of natural compounds.
DOI
10.33263/briac116.1497414985
Natural products
2021
Omoboyowa, D. A., Joshua, P. E., Nwodo, O. C., Saibu, O. A., et al. · EC Pharmacology and Toxicology
Tithonia diversifolia (Hemsl) A. Gray fractions enhanced anti-plasmodial efficacy of chloroquine in resistant Plasmodium yoelii infected mice.
Natural products
2021
Omoboyowa, D. A., Omomule, O. M., Balogun, T. A., Saibu, O. A., Matibemu, D. S. · Phytomedicine Plus
Protective potential of ethylacetate extract of Abrus precatorius (Linn) seeds against HCl/EtOH-induced gastric ulcer via proinflammatory regulation: in vivo and in silico study.
DOI
10.1016/j.phyplu.2021.100145
Natural products
2020
Omoboyowa, D. A., Balogun, T. A., Saibu, O. A. · J. Comput Sci Syst Biol.
Inhibitory potential of phyto-constituents from sorghum stem on neuro-modulatory enzymes: a computational approach.
Prostate cancer
2021
Omoboyowa, D. A., Balogun, T. A., Saibu, O. A., et al. · Biology, Methods and Protocols
Structure-based discovery of selective CYP17A1 inhibitors for castration-resistant prostate cancer treatment.
DOI
10.1093/biomethods/bpab026